News for Healthier Living

Study Sheds Light on How BRCA1 Gene Mutations Fuel Breast Cancer

At a glance: A new study in mice explains how even a single faulty copy of the BRCA1 gene can fuel tumor growth. The findings suggest the dominant "two-hit" hypothesis of cancer development may not tell the full story behind how cancer arises. Study identifies cellular changes that prime cancer-related genes for action and render cells vulnerable to tumor growth. The findings can inform new treatments that block the priming effect to prevent breast cancer formation.

November 11, 2024


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