News for Healthier Living

Brain Pathway Links Inflammation to Loss of Motivation, Energy in Advanced Cancer

Researchers at WashU Medicine identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study they describe a brain pathway that starts with neurons (labeled in green, above) that sense inflammation signals, and the researchers were able to treat the loss of motivation by blocking this pathway.

April 10, 2025


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