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Johns Hopkins Medicine Researchers Find Early Success Using Endometrial mRNA Therapy to Treat Infertility

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine -- which designs nanotechnology-based platforms for clinical translation across specialties -- developed a strategy for delivering therapeutic messenger RNA (mRNA) to the inner lining of the uterus (endometrium) in mice via modified lipid nanoparticles (LNPs), which are small capsules made of fatty molecules.

January 19, 2026


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