News for Healthier Living

A Protein Thought to Play a Supporting Role in DNA Replication Actually Facilitates the Whole Process

Cells must faithfully copy their DNA before dividing, a task carried out by polymerases that rely on clamp-like proteins to tether them to the genome. New research shows that one such protein doesn't just play a catalytic role as a clamp-loader. It also stabilizes the process as it moves the length of the DNA strand. The findings revise our understanding of the fine details of DNA replication and may have implications for human disease.

January 29, 2026


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